Phos-tag™ is a phosphate-binding molecule designed for the selective detection and separation of phosphorylated proteins and peptides. By specifically capturing phosphate groups, Phos-tag™ enables researchers to distinguish phosphorylated and non-phosphorylated forms of proteins with high resolution.

Commonly used in SDS-PAGE applications (Phos-tag™ SDS-PAGE), the reagent slows the migration of phosphorylated proteins during electrophoresis, allowing clear visualization of phosphorylation states without the need for phospho-specific antibodies. This makes it a powerful tool for studying signal transduction pathways, kinase activity, protein regulation, and post-translational modifications.

Phos-tag™ technology supports reliable phosphoprotein analysis in molecular biology, biochemistry, and cell signaling research, offering enhanced sensitivity, specificity, and reproducibility for advanced life science applications.